Um novo produto natural derivado da oxazolina, chamado aeglemarmelosina (1), juntamente com oito compostos conhecidos (2-9), foi isolado a partir de raízes e ramos de Aegle marmelos. Os compostos 1-6 foram isolados das raízes e 7-9 dos galhos. Os compostos 5 e 6 também foram encontrados nos galhos. Todas as estruturas foram caracterizadas por métodos espectroscópicos de RMN uni e bidimensionais

A new natural product oxazoline derivative named aeglemarmelosine (1) along with eight known compounds (2-9) were isolated from roots and twigs of Aegle marmelos. Compounds 1-6 were isolated from the roots whereas compounds 7-9 were obtained from twigs. Compounds 5 and 6 were also detected from the twigs. All structures were characterized by extensive 1D and 2D NMR spectroscopic methods.

Duas novas cumarinas, Clausenalansimin A (5) e B (9), juntamente com sete cumarinas conhecidas (1-4 e 6-8), foram isoladas de galhos de Clausena lansium. Todos os compostos foram determinados por métodos espectroscópicos. Alguns dos compostos isolados apresentaram citotoxicidade contra linhagens de células humanas cancerígenas (KB, MCF7 e NCI-H187).

Two new coumarins namely Clausenalansimin A (5) and B (9) together with seven known coumarins (1-4 and 6-8), were isolated from twigs of Clausena lansium. All compounds were determined by spectroscopic methods. Some of isolates had cytotoxicity against human cancer cell lines (KB, MCF7 and NCI-H187).

Uma cumarina inédita, mammea E/BB ciclo D (1), juntamente com cinco compostos conhecidos, mammea E/BA ciclo D (2), suragina C (3), terapina B (4), 1,7-dihidroxixantona (5) e 1-hidróxi-5-metoxyxantona (6), foram isolados de sementes de Mammea siamensis. Suas estruturas foram caracterizadas usando dados de RMN 1D e 2D. Suragina C e terapina B mostraram atividade citotóxica contra adenocarcinoma de mama (MCF-7), câncer cervical humano (HeLa), câncer de colon (HT-29) e câncer oral humano (KB).

A new coumarin, mammea E/BB cyclo D (1), together with five known compounds, mammea E/BA cyclo D (2), suragin C (3), therapin B (4), 1,7-dihydroxyxanthone (5) and 1-hydroxy-5-methoxyxanthone (6), were isolated from the seeds of Mammea siamensis. Their structures were characterized using 1D and 2D NMR spectral data. Suragin C and therapin B showed cytotoxic activity against breast adenocarcinoma (MCF-7), human cervical cancer (HeLa), colon cancer (HT-29) and human oral cancer (KB).